Nonsurgical Treatment for Vocal Fold Leukoplakia: An Analysis of 178 Cases

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Nonsurgical Treatment for Vocal Fold Leukoplakia: An Analysis of 178 Cases

OBJECTIVE To assess the effectiveness and identify vocal fold leukoplakia types appropriate for nonsurgical treatment. METHODS The vocal fold leukoplakia in 178 patients was divided by gross appearance into three subtypes: flat and smooth, elevated and smooth, and rough. All patients received nonsurgical treatment including smoking and drinking cessation, voice rest, omeprazole, and Chinese m...

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Genetic characterization of vocal fold lesions: leukoplakia and carcinoma.

OBJECTIVES/HYPOTHESIS Malignant transformation of laryngeal keratosis has been reported in a substantial subset of patients, yet reliable criteria for predicting patients most at risk have yet to be determined. Current methods for determining dysplasia ratings are susceptible to errors in biopsy sampling and interpretation. An understanding of the genetic underpinnings of the progression of voc...

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Classification of vocal fold leukoplakia by clinical scoring.

BACKGROUND Vocal cord leukoplakia comprises a variety of lesions. The purpose of this study was to stratify vocal leukoplakias before surgery. METHODS Patients with an initial diagnosis of vocal leukoplakia who underwent surgical excision at a tertiary referral center in Taiwan were recruited for this study. Their clinical records, including age, sex, preoperative laryngoscopic images in the ...

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A Review of the Nonsurgical Treatment of Oral Leukoplakia

The aim of this paper was to assess the nonsurgical treatment of oral leukoplakia (OL). A medline search from 1983 to 2009 was conducted. The topical or systemic nonsurgical treatments or combination of both was reviewed. The primary outcomes of interest were clinical resolution, malignant transformation, follow-up, and recurrence of OL. Studies showed a rate higher than 50% of clinical resolut...

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Glass ionomer application for vocal fold augmentation: Histopathological analysis on rabbit vocal fold.

OBJECTIVES/HYPOTHESIS The aim of this study was to investigate the use of glass ionomer cement (GIC) as an injection material for vocal fold augmentation and to evaluate the biocompatibility of the material. STUDY DESIGN Ten adult New Zealand rabbits were used. METHODS Under general anesthesia, 0.1-cc GIC was injected to one vocal fold and the augmentation of vocal fold was observed. No inj...

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ژورنال

عنوان ژورنال: BioMed Research International

سال: 2017

ISSN: 2314-6133,2314-6141

DOI: 10.1155/2017/6958250